- Product Details
Keywords
- Bay 43-9006
- Bay43-9006
- Sorafenib RECHEMS
Quick Details
- ProName: Sorafenib
- CasNo: 284461-73-0
- Appearance: solid
- Application: Medicinal Chemistry 、 Biomedicine、 Pha...
- DeliveryTime: In-stock
- PackAge: Bottle and bag according to customer
- Port: Shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: Stored in well-closed containers
- Transportation: By express
- LimitNum: 0 Metric Ton
- Valid Period: 3 years when properly stored
Superiority
1.About this compound, custom synthetic service could be provided and COA/HPLC/HNMR is available.
2.Professional synthesis laboratory and production base.
3.Strong synthesis team and service team.
4.Professional data management system.
5.We provide the professional test date and product information
6.Rich shipping methods,ex. Fedex,DHL,TNT,BY SEA and BY AIR.
7. We can accept various payment methods,Paypal,T/T, etc.
8.Professional packaging can be according the customers’requirment.
9.Product application: Medicinal Chemistry 、 Biomedicine、 Pharmaceutical intermediate、 Chemistry experiment 、Biological experiments 、Chemical reagent、 For R&D use only.
Details
Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator.